Assembly of free-standing polypeptide films via the synergistic combination of hyperbranched macroinitiators, the grafting-from approach, and cross-chain termination

SH Wibowo; EHH Wong; A Sulistio; SN Guntari; A Blencowe; F Caruso; GG Qiao

Journal article

Assembly of free-standing polypeptide films via the synergistic combination of hyperbranched macroinitiators, the grafting-from approach, and cross-chain termination

SH Wibowo, EHH Wong, A Sulistio, SN Guntari, A Blencowe, F Caruso, GG Qiao

Advanced Materials | WILEY-V C H VERLAG GMBH | Published : 2013

DOI: 10.1002/adma.201301132

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Abstract

Cross-linked polypeptide-based films are fabricated via a novel and robust method employing surface-initiated ring opening polymerization of α-amino acid N-carboxyanhydrides (NCA-ROP). The judicious combination of amine-based hyperbranched macroinitiators and benzyl ester-protected NCA derivatives promotes network formation by cross-chain terminations, which allows the formation of stable cross-linked peptide-based capsules in a one-pot system. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

University of Melbourne Researchers

Frank Caruso Author

Greg Qiao Author

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Funding Acknowledgements

The authors acknowledge the Australian Research Council under the Australian Laureate Fellowship (FL120100030, F.C.), Future Fellowship (FT110100411, G.G.Q.) and Discovery Project (DP130101846, F.C., G.G.Q.) schemes for financial support of this work.